Screen-readers do not pick up on the position of elements on a page. When organising content and building the layout, the designer should take a logical linear approach to the elements’ visual hierarchy, allowing the most important content to be discovered easily before the calls to action. The screen reader will communicate the information in the order it is displayed on the page so for it not to be missed, it must be organised in a logical layout.
Keeping content simple with short line length and consistent left alignment will enhance legibility for everyone. Specifically, users with dyslexia or on the autistic spectrum will process information more effectively if it’s presented in a consistent pattern.
From a structure perspective, a quick win can be achieved with the inclusion of a sitemap to guarantee the user will find what they’re looking for easily, without having to scroll through pages and pages of overwhelming content. This simple step would enhance the experience of many users who may otherwise find it difficult to find their way around a complex navigation.